Superior Treg-Expanding Properties of a Novel Dual-Acting Cytokine Fusion Protein

• Hoofdauteurs: Tanja Padutsch (Auteur), Maksim Sendetski (Auteur), Carina Huber (Auteur), Nathalie Peters (Auteur), Klaus Pfizenmaier (Auteur), John R. Bethea (Auteur), Roland E. Kontermann (Auteur), Roman Fischer (Auteur)
• Formaat: Boek
• Gepubliceerd in: Frontiers Media S.A., 2019-12-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

Autoimmune diseases are caused by uncontrolled endogenous immune responses against healthy cells. They may develop due to an impaired function of regulatory T cells (Tregs), which normally suppress self-specific effector immune cells. Interleukin 2 (IL-2) and tumor necrosis factor (TNF) have been id...