Superior Treg-Expanding Properties of a Novel Dual-Acting Cytokine Fusion Protein
Autoimmune diseases are caused by uncontrolled endogenous immune responses against healthy cells. They may develop due to an impaired function of regulatory T cells (Tregs), which normally suppress self-specific effector immune cells. Interleukin 2 (IL-2) and tumor necrosis factor (TNF) have been id...
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Frontiers Media S.A.,
2019-12-01T00:00:00Z.
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