Genetic variants of genes involved in thiopurine metabolism pathway are associated with 6-mercaptopurine toxicity in pediatric acute lymphoblastic leukemia patients from Ethiopia

Introduction: Genetic variation in the thiopurine S-methyltransferase (TPMT) gene by and large predicts variability in 6-mercaptopurine (6-MP) related toxicities. However, some individuals without genetic variants in TPMT still develop toxicity that necessitates 6-MP dose reduction or interruption....

Full description

Saved in:
Bibliographic Details
Main Authors: Awol Mekonnen Ali (Author), Haileyesus Adam (Author), Daniel Hailu (Author), Ephrem Engidawork (Author), Rawleigh Howe (Author), Teferra Abula (Author), Marieke J. H. Coenen (Author)
Format: Book
Published: Frontiers Media S.A., 2023-05-01T00:00:00Z.
Subjects:
Online Access:Connect to this object online.
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

Connect to this object online.

3rd Floor Main Library

Holdings details from 3rd Floor Main Library
Call Number: A1234.567
Copy 1 Available