Pravastatin Prevents Increases in Activity of Metalloproteinase-2 and Oxidative Stress, and Enhances Endothelium-Derived Nitric Oxide-Dependent Vasodilation in Gestational Hypertension

• Автори: Cristal Jesus Toghi (Автор), Laisla Zanetoni Martins (Автор), Leonardo Lopes Pacheco (Автор), Edileia Souza Paula Caetano (Автор), Bruna Rahal Mattos (Автор), Elen Rizzi (Автор), Carlos Alan Dias-Junior (Автор)
• Формат: Книга
• Опубліковано: MDPI AG, 2023-04-01T00:00:00Z.
• Предмети: article
• Онлайн доступ: Connect to this object online.

Pre-eclampsia (PE) is a hypertensive disorder of pregnancy and has been associated with placental growth restriction. The pre-eclamptic placenta releases free radicals to maternal circulation, thus increasing oxidative stress. An impaired redox state leads to reduction in circulating nitric oxide (N...