Pravastatin Prevents Increases in Activity of Metalloproteinase-2 and Oxidative Stress, and Enhances Endothelium-Derived Nitric Oxide-Dependent Vasodilation in Gestational Hypertension

• Hauptverfasser: Cristal Jesus Toghi (Verfasst von), Laisla Zanetoni Martins (Verfasst von), Leonardo Lopes Pacheco (Verfasst von), Edileia Souza Paula Caetano (Verfasst von), Bruna Rahal Mattos (Verfasst von), Elen Rizzi (Verfasst von), Carlos Alan Dias-Junior (Verfasst von)
• Format: Buch
• Veröffentlicht: MDPI AG, 2023-04-01T00:00:00Z.
• Schlagworte: article
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Pre-eclampsia (PE) is a hypertensive disorder of pregnancy and has been associated with placental growth restriction. The pre-eclamptic placenta releases free radicals to maternal circulation, thus increasing oxidative stress. An impaired redox state leads to reduction in circulating nitric oxide (N...