Nitric Oxide-Donating Genistein Prodrug: Design, Synthesis, and Bioactivity on MC3T3-E1 Cells

• Hauptverfasser: Jiepin Wang (Verfasst von), Fujun Shang (Verfasst von), Ru Jiang (Verfasst von), Li Liu (Verfasst von), Siwang Wang (Verfasst von), Jin Hou (Verfasst von), Menglei Huan (Verfasst von), Qibing Mei (Verfasst von)
• Format: Buch
• Veröffentlicht: Elsevier, 2007-01-01T00:00:00Z.
• Schlagworte: article
• Online-Zugang: Connect to this object online.

To find a more potent alternative with less estrogen-related side effects for hormone replacement therapy, we designed and synthesized a nitric oxide (NO)-releasing prodrug of genistein, named NO-donating genistein (NO-G). The characteristics of NO-G were determined by melting point, NMR spectroscop...