Peg-Grafted Liposomes for L-Asparaginase Encapsulation

• Prif Awduron: Marina de Souza Guimarães (Awdur), Jorge Javier Muso Cachumba (Awdur), Cecilia Zorzi Bueno (Awdur), Karin Mariana Torres-Obreque (Awdur), Grace Verónica Ruiz Lara (Awdur), Gisele Monteiro (Awdur), Leandro Ramos Souza Barbosa (Awdur), Adalberto Pessoa (Awdur), Carlota de Oliveira Rangel-Yagui (Awdur)
• Fformat: Llyfr
• Cyhoeddwyd: MDPI AG, 2022-08-01T00:00:00Z.
• Pynciau: article
• Mynediad Ar-lein: Connect to this object online.

L-asparaginase (ASNase) is an important biological drug used to treat Acute Lymphoblastic Leukemia (ALL). It catalyzes the hydrolysis of L-asparagine (Asn) in the bloodstream and, since ALL cells cannot synthesize Asn, protein synthesis is impaired leading to apoptosis. Despite its therapeutic impor...