Peg-Grafted Liposomes for L-Asparaginase Encapsulation

• Główni autorzy: Marina de Souza Guimarães (Autor), Jorge Javier Muso Cachumba (Autor), Cecilia Zorzi Bueno (Autor), Karin Mariana Torres-Obreque (Autor), Grace Verónica Ruiz Lara (Autor), Gisele Monteiro (Autor), Leandro Ramos Souza Barbosa (Autor), Adalberto Pessoa (Autor), Carlota de Oliveira Rangel-Yagui (Autor)
• Format: Książka
• Wydane: MDPI AG, 2022-08-01T00:00:00Z.
• Hasła przedmiotowe: article
• Dostęp online: Connect to this object online.

L-asparaginase (ASNase) is an important biological drug used to treat Acute Lymphoblastic Leukemia (ALL). It catalyzes the hydrolysis of L-asparagine (Asn) in the bloodstream and, since ALL cells cannot synthesize Asn, protein synthesis is impaired leading to apoptosis. Despite its therapeutic impor...