Astaxanthin Ameliorated Parvalbumin-Positive Neuron Deficits and Alzheimer's Disease-Related Pathological Progression in the Hippocampus of AppNL-G-F/NL-G-F Mice

• Главные авторы: Nobuko Hongo (Автор), Yusaku Takamura (Автор), Hiroshi Nishimaru (Автор), Jumpei Matsumoto (Автор), Kazuyuki Tobe (Автор), Takashi Saito (Автор), Takaomi C. Saido (Автор), Hisao Nishijo (Автор)
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• Опубликовано: Frontiers Media S.A., 2020-03-01T00:00:00Z.
• Предметы: article
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Growing evidence suggests that oxidative stress due to amyloid β (Aβ) accumulation is involved in Alzheimer's disease (AD) through the formation of amyloid plaque, which leads to hyperphosphorylation of tau, microglial activation, and cognitive deficits. The dysfunction or phenotypic loss of pa...