Astaxanthin Ameliorated Parvalbumin-Positive Neuron Deficits and Alzheimer's Disease-Related Pathological Progression in the Hippocampus of AppNL-G-F/NL-G-F Mice

• Main Authors: Nobuko Hongo (Author), Yusaku Takamura (Author), Hiroshi Nishimaru (Author), Jumpei Matsumoto (Author), Kazuyuki Tobe (Author), Takashi Saito (Author), Takaomi C. Saido (Author), Hisao Nishijo (Author)
• Format: Book
• Published: Frontiers Media S.A., 2020-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Growing evidence suggests that oxidative stress due to amyloid β (Aβ) accumulation is involved in Alzheimer's disease (AD) through the formation of amyloid plaque, which leads to hyperphosphorylation of tau, microglial activation, and cognitive deficits. The dysfunction or phenotypic loss of pa...