Ulinastatin Inhibits Osteoclastogenesis and Suppresses Ovariectomy-Induced Bone Loss by Downregulating uPAR

• Asıl Yazarlar: Jun-ming Huang (Yazar), Ran-yue Ren (Yazar), Yuan Bao (Yazar), Jia-chao Guo (Yazar), Wei Xiang (Yazar), Xing-zhi Jing (Yazar), Jia Shi (Yazar), Guo-xiang Zhang (Yazar), Long Li (Yazar), Yong Tian (Yazar), Hao Kang (Yazar), Feng-jin Guo (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Frontiers Media S.A., 2018-09-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Recent studies indicate that uPAR acts a crucial part in cell migration and the modulation of bone homeostasis. As a natural serine protease inhibitor, ulinastatin owns the capacity to reduce proinflammatory factors, downregulate the activation of NF-κB and mitogen-activated protein kinases (MAPKs)...