3,3'-Diindolylmethane improves antitumor immune responses of PD-1 blockade via inhibiting myeloid-derived suppressor cells

• Main Authors: Qi Sun (Author), Lin Xiao (Author), Zhiying Cui (Author), Yaping Yang (Author), Junting Ma (Author), Zhen Huang (Author), Junfeng Zhang (Author), Jiangning Chen (Author)
• Format: Book
• Published: BMC, 2022-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Immune checkpoint inhibitors that target programmed cell death protein 1 (PD-1) have obtained encouraging results, but a fraction of tumor patients failed to respond to anti-PD-1 treatment due to the existence of multiple immune suppressive elements such as myeloid-derived suppre...