3,3'-Diindolylmethane improves antitumor immune responses of PD-1 blockade via inhibiting myeloid-derived suppressor cells

• Hoofdauteurs: Qi Sun (Auteur), Lin Xiao (Auteur), Zhiying Cui (Auteur), Yaping Yang (Auteur), Junting Ma (Auteur), Zhen Huang (Auteur), Junfeng Zhang (Auteur), Jiangning Chen (Auteur)
• Formaat: Boek
• Gepubliceerd in: BMC, 2022-06-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

Abstract Background Immune checkpoint inhibitors that target programmed cell death protein 1 (PD-1) have obtained encouraging results, but a fraction of tumor patients failed to respond to anti-PD-1 treatment due to the existence of multiple immune suppressive elements such as myeloid-derived suppre...