Development and In Vitro Evaluation of Controlled Release Viagra<sup>®</sup> Containing Poloxamer-188 Using Gastroplus<sup>™</sup> PBPK Modeling Software for In Vivo Predictions and Pharmacokinetic Assessments
Sildenafil is the active substance in Viagra<sup>®</sup> tablets, which is approved by the FDA to treat sexual dysfunction in men. Poor solubility and short half-life, however, can limit the span of its effectiveness. Therefore, this study focused on an oral controlled release matrix sys...
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| Main Authors: | , , |
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| Format: | Book |
| Published: |
MDPI AG,
2021-05-01T00:00:00Z.
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| Call Number: |
A1234.567 |
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| Copy 1 | Available |