CASK Mediates Oxidative Stress-Induced Microglial Apoptosis-Inducing Factor-Independent Parthanatos Cell Death via Promoting PARP-1 Hyperactivation and Mitochondrial Dysfunction

• প্রধান লেখক: Keith Jun Hao Cheong (লেখক), Duen-Yi Huang (লেখক), Ponarulselvam Sekar (লেখক), Rou Jhen Chen (লেখক), Irene Han-Juo Cheng (লেখক), Chi-Ming Chan (লেখক), Yuan-Shen Chen (লেখক), Wan-Wan Lin (লেখক)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: MDPI AG, 2024-03-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

Calcium/calmodulin-dependent serine protein kinase (CASK) is a scaffold protein and plays critical roles in neuronal synaptic formation and brain development. Previously, CASK was shown to associate with EGFR to maintain the vulval cell differentiation in <i>C. elegans</i>. In this study...