Dominant inhibition of Fas ligand-mediated apoptosis due to a heterozygous mutation associated with autoimmune lymphoproliferative syndrome (ALPS) Type Ib

• Главные авторы: McDonald Jay M (Автор), Reddy Vishnu (Автор), Makris Christopher (Автор), Dale Janet K (Автор), Zheng Lixin (Автор), Atkinson T Prescott (Автор), Pan George (Автор), Bi Lilia L (Автор), Siegel Richard M (Автор), Puck Jennifer M (Автор), Lenardo Michael J (Автор), Straus Stephen E (Автор)
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• Опубликовано: BMC, 2007-07-01T00:00:00Z.
• Предметы: article
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<p>Abstract</p> <p>Background:</p> <p>Autoimmune lymphoproliferative syndrome (ALPS) is a disorder of lymphocyte homeostasis and immunological tolerance due primarily to genetic defects in Fas (CD95/APO-1; <it>TNFRSF6</it>), a cell surface receptor that regu...