Regulation of IκBα expression involves both NF-κB and the MAP kinase signaling pathways

• Päätekijät: Sambucetti Lidia C (Tekijä), Zhu Lingyun (Tekijä), Ahsan Muhammad H (Tekijä), Zhang Ning (Tekijä), Purchio Anthony F (Tekijä), West David B (Tekijä)
• Aineistotyyppi: Kirja
• Julkaistu: BMC, 2005-10-01T00:00:00Z.
• Aiheet: article
• Linkit: Connect to this object online.

<p>Abstract</p> <p>IκBα is an inhibitor of the nuclear transcription factor NF-κB. Binding of IκBα to NF-κB inactivates the transcriptional activity of NF-κB. Expression of IκBα itself is regulated by NF-κB, which provides auto-regulation of this signaling pathway. Here we present...