Regulation of IκBα expression involves both NF-κB and the MAP kinase signaling pathways

• Glavni autori: Sambucetti Lidia C (Autor), Zhu Lingyun (Autor), Ahsan Muhammad H (Autor), Zhang Ning (Autor), Purchio Anthony F (Autor), West David B (Autor)
• Format: Knjiga
• Izdano: BMC, 2005-10-01T00:00:00Z.
• Teme: article
• Online pristup: Connect to this object online.

<p>Abstract</p> <p>IκBα is an inhibitor of the nuclear transcription factor NF-κB. Binding of IκBα to NF-κB inactivates the transcriptional activity of NF-κB. Expression of IκBα itself is regulated by NF-κB, which provides auto-regulation of this signaling pathway. Here we present...