A phase I study to evaluate the safety, tolerability, and pharmacokinetics of a novel, potent GABA analog HSK16149 in healthy Chinese subjects

• Автори: Qian Chen (Автор), Qingqing Wu (Автор), Rong Song (Автор), Yating Wang (Автор), Mengqi Zhang (Автор), Fangqiong Li (Автор), Weifang Zeng (Автор), Wei Wang (Автор), Jingying Jia (Автор), Chen Yu (Автор), Yanmei Liu (Автор)
• Формат: Книга
• Опубліковано: Frontiers Media S.A., 2023-12-01T00:00:00Z.
• Предмети: article
• Онлайн доступ: Connect to this object online.

Purpose: HSK16149 is a novel, potent gamma-aminobutyric acid (GABA) analog for the treatment of neuropathic pain. This study aimed to evaluate the safety, tolerability, and pharmacokinetics of HSK16149 after single and multiple doses in healthy Chinese subjects.Methods: The randomized, double-blind,...