Non-Human Primate Blood-Brain Barrier and In Vitro Brain Endothelium: From Transcriptome to the Establishment of a New Model

• Hoofdauteurs: Catarina Chaves (Auteur), Tuan-Minh Do (Auteur), Céline Cegarra (Auteur), Valérie Roudières (Auteur), Sandrine Tolou (Auteur), Gilbert Thill (Auteur), Corinne Rocher (Auteur), Michel Didier (Auteur), Dominique Lesuisse (Auteur)
• Formaat: Boek
• Gepubliceerd in: MDPI AG, 2020-10-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

The non-human primate (NHP)-brain endothelium constitutes an essential alternative to human in the prediction of molecule trafficking across the blood-brain barrier (BBB). This study presents a comparison between the NHP transcriptome of freshly isolated brain microcapillaries and in vitro-selected...