Quinazolin-4-one derivatives lacking toxicity-producing attributes as glucokinase activators: design, synthesis, molecular docking, and in-silico ADMET prediction
Abstract Background A small library of quinazolin-4-one clubbed thiazole acetates/acetamides lacking toxicity-producing functionalities was designed, synthesized, and evaluated for antidiabetic potential as glucokinase activators (GKA). Molecular docking studies were done in the allosteric site of t...
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| Main Authors: | , , , , , , , |
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| Format: | Book |
| Published: |
SpringerOpen,
2019-12-01T00:00:00Z.
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| Subjects: | |
| Online Access: | Connect to this object online. |
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