Docking studies on novel analogs of quinolones against DNA gyrase of Escherichia coli

• Main Authors: Cristian Davila (Author), Lorena Llach (Author), Guillermo Salgado-Moran (Author), Rodrigo Ramirez-Tagle (Author)
• Format: Bog
• Udgivet: GarVal Editorial Ltda., 2018-09-01T00:00:00Z.
• Fag: article
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Context: Bacterial resistance to antibiotics is the inevitable consequence of the use of antimicrobial agents. Thus, quinolones are an important class of antibacterials; these agents generally consist of a 1-subtituted-1,4-dihydro-4-oxopyridine-3-carboxylic acid moiety combined with an aromatic or h...