Suppression of NRF2 Activity by HIF-1α Promotes Fibrosis after Ischemic Acute Kidney Injury

• Váldodahkkit: Corry D. Bondi (Dahkki), Brittney M. Rush (Dahkki), Hannah L. Hartman (Dahkki), Jiaxuan Wang (Dahkki), Mohammad M. Al-Bataineh (Dahkki), Rebecca P. Hughey (Dahkki), Roderick J. Tan (Dahkki)
• Materiálatiipa: Girji
• Almmustuhtton: MDPI AG, 2022-09-01T00:00:00Z.
• Fáttát: article
• Liŋkkat: Connect to this object online.

Acute kidney injury (AKI) is a rapid decline in renal function and can occur after ischemia/reperfusion injury (IRI) to the tubular epithelia. The nuclear factor erythroid-2-related factor 2 (NRF2) pathway protects against AKI and AKI-to-chronic kidney disease (CKD) progression, but we previously de...