Genetic analysis of polymorphisms in the kalirin gene for association with age-at-onset in European Huntington disease patients

• Главные авторы: Tsai Yu-Chun (Автор), Metzger Silke (Автор), Riess Olaf (Автор), Soehn Anne S (Автор), Nguyen Huu (Автор)
• Формат: ‌
• Опубликовано: BMC, 2012-06-01T00:00:00Z.
• Предметы: article
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<p>Abstract</p> <p>Background</p> <p>Huntington disease (HD) is caused by an expanded CAG repeat in the <it>HD</it> gene. Although the length of the CAG repeat strongly correlates with the age-at-onset (AAO), AAO in HD individuals may differ dramatically in...