Genetic analysis of polymorphisms in the kalirin gene for association with age-at-onset in European Huntington disease patients

• Main Authors: Tsai Yu-Chun (Author), Metzger Silke (Author), Riess Olaf (Author), Soehn Anne S (Author), Nguyen Huu (Author)
• Format: Book
• Published: BMC, 2012-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>Huntington disease (HD) is caused by an expanded CAG repeat in the <it>HD</it> gene. Although the length of the CAG repeat strongly correlates with the age-at-onset (AAO), AAO in HD individuals may differ dramatically in...