Multifunctional approach with LHRH-mediated PLGA nanoconjugate for site-specific codelivery of curcumin and BCL2 siRNA in mice lung cancer

• Váldodahkkit: Madhuchandra Lahan (Dahkki), Trideep Saikia (Dahkki), Kalpajit Dutta (Dahkki), Rinku Baishya (Dahkki), Alakesh Bharali (Dahkki), Sunayana Baruah (Dahkki), Rituraj Bharadwaj (Dahkki), Subhash Medhi (Dahkki), Bhanu P. Sahu (Dahkki)
• Materiálatiipa: Girji
• Almmustuhtton: SpringerOpen, 2024-11-01T00:00:00Z.
• Fáttát: article
• Liŋkkat: Connect to this object online.

Abstract Background Lung cancer remains a leading cancer type, but current chemotherapy is limited by issues including poor drug delivery, toxicity, and resistance. To address these challenges, we developed a novel PLGA-PEG-LHRH (PPL) nanoconjugate system for improved drug delivery. Curcumin, known...