The removal of multiplicative, systematic bias allows integration of breast cancer gene expression datasets - improving meta-analysis and prediction of prognosis

• Asıl Yazarlar: Pepper Stuart D (Yazar), Okoniewski Michal J (Yazar), Hey Yvonne (Yazar), Smethurst Graeme J (Yazar), Sims Andrew H (Yazar), Howell Anthony (Yazar), Miller Crispin J (Yazar), Clarke Robert B (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: BMC, 2008-09-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>The number of gene expression studies in the public domain is rapidly increasing, representing a highly valuable resource. However, dataset-specific bias precludes meta-analysis at the raw transcript level, even when the RNA is from...