The removal of multiplicative, systematic bias allows integration of breast cancer gene expression datasets - improving meta-analysis and prediction of prognosis

• Päätekijät: Pepper Stuart D (Tekijä), Okoniewski Michal J (Tekijä), Hey Yvonne (Tekijä), Smethurst Graeme J (Tekijä), Sims Andrew H (Tekijä), Howell Anthony (Tekijä), Miller Crispin J (Tekijä), Clarke Robert B (Tekijä)
• Aineistotyyppi: Kirja
• Julkaistu: BMC, 2008-09-01T00:00:00Z.
• Aiheet: article
• Linkit: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>The number of gene expression studies in the public domain is rapidly increasing, representing a highly valuable resource. However, dataset-specific bias precludes meta-analysis at the raw transcript level, even when the RNA is from...