METTL14-mediated m6A modification enhances USP22-ERα axis to drive breast cancer malignancy

• প্রধান লেখক: Xuefen Zhuang (লেখক), Shusha Yin (লেখক), Ji Cheng (লেখক), Wenshuang Sun (লেখক), Zesen Fang (লেখক), Yujie Xiang (লেখক), E.-ying Peng (লেখক), Yu Yao (লেখক), Yuting Li (লেখক), Xiaoyue He (লেখক), Li Lu (লেখক), Yuanfei Deng (লেখক), Hongbiao Huang (লেখক), Gengxi Cai (লেখক), Yuning Liao (লেখক)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: Elsevier, 2024-12-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

The abundance and activity of estrogen receptor alpha (ERα) are tightly regulated by ubiquitin-specific peptidase 22 (USP22) during the progression of breast cancer (BCa). However, the post-transcriptional modifications on the USP22-ERα axis remain elusive. N6-methyladenosine (m6A) is critical to mo...