Design, Synthesis, anticancer evaluation and in silico studies of 2,4,6-trimethoxychalcone derivatives

• Autori principali: Tong Li (Autore), Weiwei Li (Autore), Xianjing Yang (Autore), Gong Chen (Autore), Xiaobao Jin (Autore), Weiqiang Chen (Autore), Lianbao Ye (Autore)
• Natura: Libro
• Pubblicazione: Elsevier, 2023-01-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

Chalcone, a common chemical scaffold of many naturally occurring compounds, has been widely used as an effective template for drug discovery due to its broad biological activities. In this study, a series of chalcone derivatives were designed and synthesized based on the hybridization of 1-(2,4,6-tr...