Design, Synthesis, anticancer evaluation and in silico studies of 2,4,6-trimethoxychalcone derivatives

• Main Authors: Tong Li (Author), Weiwei Li (Author), Xianjing Yang (Author), Gong Chen (Author), Xiaobao Jin (Author), Weiqiang Chen (Author), Lianbao Ye (Author)
• Format: Book
• Published: Elsevier, 2023-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Chalcone, a common chemical scaffold of many naturally occurring compounds, has been widely used as an effective template for drug discovery due to its broad biological activities. In this study, a series of chalcone derivatives were designed and synthesized based on the hybridization of 1-(2,4,6-tr...