Co-Delivery of siRNA and Chemotherapeutic Drug Using 2C5 Antibody-Targeted Dendrimer-Based Mixed Micelles for Multidrug Resistant Cancers

• Үндсэн зохиолчид: Satya Siva Kishan Yalamarty (Зохиогч), Nina Filipczak (Зохиогч), Xiang Li (Зохиогч), Tanvi Vinod Pathrikar (Зохиогч), Colin Cotter (Зохиогч), Vladimir P. Torchilin (Зохиогч)
• Формат: Ном
• Хэвлэсэн: MDPI AG, 2022-07-01T00:00:00Z.
• Нөхцлүүд: article
• Онлайн хандалт: Connect to this object online.

Multidrug resistance (MDR) observed in tumors significantly hinders the efficacy of chemotherapy. Downregulation of efflux proteins, such as P-glycoprotein (P-gp), using small interfering RNA (siRNA) can be an effective way to minimize the resistance in tumors. In this study, monoclonal antibody 2C5...