Orally Disintegrating Tablets Containing Melt Extruded Amorphous Solid Dispersion of Tacrolimus for Dissolution Enhancement

In order to improve the aqueous solubility and dissolution of Tacrolimus (TAC), amorphous solid dispersions of TAC were prepared by hot melt extrusion with three hydrophilic polymers, Polyvinylpyrrolidone vinyl acetate (PVP VA64), Soluplus® and Hydroxypropyl Cellulose (HPC), at a drug loading of 10%...

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Bibliographic Details
Main Authors: Poovizhi Ponnammal (Author), Parijat Kanaujia (Author), Yin Yani (Author), Wai Kiong Ng (Author), Reginald B. H. Tan (Author)
Format: Book
Published: MDPI AG, 2018-03-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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