Hereditary Tyrosinemia Type 1 in Jordan: A Retrospective Study

• Main Authors: Noor A. Megdadi (Author), Ahmad K. Almigdad (Author), Mo'men O. Alakil (Author), Shahrazad M. Alqiam (Author), Sumaia G. Rababah (Author), Moshera A. Dwiari (Author)
• Format: Book
• Published: Hindawi Limited, 2021-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background. Hereditary tyrosinemia type 1 (HT1) is a recessively inherited inborn error of metabolism affecting the final step of tyrosine catabolism. The accumulation of tyrosine toxic metabolites leads to progressive hepatic, renal, and neurological manifestations. Treatment of HT1 consists of tyr...