Co-inhibition of Angiotensin II Receptor and Endothelin-1 Attenuates Renal Injury in Unilateral Ureteral Obstructed Mice

• Автори: Yoon-Kyung Chang (Автор), Hyunsu Choi (Автор), Jin Young Jeong (Автор), Ki-Ryang Na (Автор), Kang Wook Lee (Автор), Dae Eun Choi (Автор)
• Формат: Книга
• Опубліковано: Karger Publishers, 2016-07-01T00:00:00Z.
• Предмети: article
• Онлайн доступ: Connect to this object online.

Background/Aims: Both endothelin-1 (ET-1) and the renin-angiotensin system (RAS) may play important roles in renal fibrosis in the obstructed kidney. However, there have been few clear demonstrations of a relationship between their activation and additive or synergistic roles in renal fibrosis. We i...