Co-inhibition of Angiotensin II Receptor and Endothelin-1 Attenuates Renal Injury in Unilateral Ureteral Obstructed Mice

• প্রধান লেখক: Yoon-Kyung Chang (লেখক), Hyunsu Choi (লেখক), Jin Young Jeong (লেখক), Ki-Ryang Na (লেখক), Kang Wook Lee (লেখক), Dae Eun Choi (লেখক)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: Karger Publishers, 2016-07-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

Background/Aims: Both endothelin-1 (ET-1) and the renin-angiotensin system (RAS) may play important roles in renal fibrosis in the obstructed kidney. However, there have been few clear demonstrations of a relationship between their activation and additive or synergistic roles in renal fibrosis. We i...