SDF-1/CXCR4 Signaling Maintains Stemness Signature in Mouse Neural Stem/Progenitor Cells

• Hoofdauteurs: Shih-Yin Ho (Auteur), Thai-Yen Ling (Auteur), Hsing-Yu Lin (Auteur), Jeffrey Tsai-Jui Liou (Auteur), Fei-Chih Liu (Auteur), I-Chun Chen (Auteur), Sue-Wei Lee (Auteur), Yu Hsu (Auteur), Dar-Ming Lai (Auteur), Horng-Huei Liou (Auteur)
• Formaat: Boek
• Gepubliceerd in: Hindawi Limited, 2017-01-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

SDF-1 and its primary receptor, CXCR4, are highly expressed in the embryonic central nervous system (CNS) and play a crucial role in brain architecture. Loss of SDF-1/CXCR4 signaling causes abnormal development of neural stem/progenitor cells (NSCs/NPCs) in the cerebellum, hippocampus, and cortex. H...