Cancer-associated fibroblasts impact the clinical outcome and treatment response in colorectal cancer via immune system modulation: a comprehensive genome-wide analysis

• Principais autores: Yu-feng Chen (Autor), Zhao-liang Yu (Autor), Min-yi Lv (Autor), Ze-rong Cai (Autor), Yi-feng Zou (Autor), Ping Lan (Autor), Xiao-jian Wu (Autor), Feng Gao (Autor)
• Formato: Livro
• Publicado em: BMC, 2021-10-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Abstract Background Cancer-associated fibroblasts (CAFs) in the tumour microenvironment are associated with poor prognosis and chemoresistance in multiple solid tumours. However, there is a lack of universal measures of CAFs in colorectal cancer (CRC). The aim of this study was to assess the utility...