Cancer-associated fibroblasts impact the clinical outcome and treatment response in colorectal cancer via immune system modulation: a comprehensive genome-wide analysis

• Main Authors: Yu-feng Chen (Author), Zhao-liang Yu (Author), Min-yi Lv (Author), Ze-rong Cai (Author), Yi-feng Zou (Author), Ping Lan (Author), Xiao-jian Wu (Author), Feng Gao (Author)
• Format: Book
• Published: BMC, 2021-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Cancer-associated fibroblasts (CAFs) in the tumour microenvironment are associated with poor prognosis and chemoresistance in multiple solid tumours. However, there is a lack of universal measures of CAFs in colorectal cancer (CRC). The aim of this study was to assess the utility...