Mannose/stearyl chloride doubly functionalized polyethylenimine as a nucleic acid vaccine carrier to promote macrophage uptake

• Główni autorzy: Lu Bai (Autor), Xiaoqi Chen (Autor), Chengyu Li (Autor), Haijun Zhou (Autor), Yantao Li (Autor), Jijun Xiao (Autor), Fen Zhang (Autor), Hua Cheng (Autor), Mengmeng Zhou (Autor)
• Format: Książka
• Wydane: Taylor & Francis Group, 2024-12-01T00:00:00Z.
• Hasła przedmiotowe: article
• Dostęp online: Connect to this object online.

Transmembrane transport remains a significant challenge for nucleic acid vaccine vectors. Promoting the ability of immune cells, such as macrophages, to capture foreign stimuli is also an effective approach to improving cross-presentation. In addition, polyethyleneimine (PEI) has gained attention in...