Mannose/stearyl chloride doubly functionalized polyethylenimine as a nucleic acid vaccine carrier to promote macrophage uptake

• Main Authors: Lu Bai (Author), Xiaoqi Chen (Author), Chengyu Li (Author), Haijun Zhou (Author), Yantao Li (Author), Jijun Xiao (Author), Fen Zhang (Author), Hua Cheng (Author), Mengmeng Zhou (Author)
• Format: Book
• Published: Taylor & Francis Group, 2024-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Transmembrane transport remains a significant challenge for nucleic acid vaccine vectors. Promoting the ability of immune cells, such as macrophages, to capture foreign stimuli is also an effective approach to improving cross-presentation. In addition, polyethyleneimine (PEI) has gained attention in...