Intestinal Metabolism of Crocin and a Pharmacokinetics and Pharmacodynamics Study in the Chronic Social Defeat Stress Mouse Model
Orally administered crocin rapidly and efficiently rescues depressive-like behaviors in depression models; however, crocin levels in the circulatory and central nervous systems are rather low. The underlying mechanism responsible for the inconsistency between pharmacokinetics and pharmacodynamics is...
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Main Authors: | Fan Xiao (Author), Yulong Song (Author), Guangji Wang (Author), Jiye Aa (Author) |
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Format: | Book |
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MDPI AG,
2024-06-01T00:00:00Z.
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Online Access: | Connect to this object online. |
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