Method development for the quantitative determination of captopril from Caco-2 cell monolayers by using LC-MS/MS

• Auteurs principaux: Liliya Logoyda (Auteur), Marjan Piponski (Auteur), Sergiy Kovalenko (Auteur), Olha Denefil (Auteur), Olha Dutchak (Auteur), Yuriy Soroka (Auteur), Svitlana Pidruchna (Auteur), Dariya Popovych (Auteur), Oleksandr Susla (Auteur)
• Format: Livre
• Publié: Pensoft Publishers, 2021-01-01T00:00:00Z.
• Sujets: article
• Accès en ligne: Connect to this object online.

Aim. Caco-2 cells are a human colon epithelial cancer cell line used as a model of human intestinal absorption of drugs and other compounds. Although compounds were used in the original Caco-2 cells monolayer assays, compounds have been replaced in most laboratories by the use of liquid chromatograp...