Role of ICAM-1 in the aggregation and adhesion of human alveolar macrophages in response to TNF-α and INF-γ

• Main Authors: Masahiro Sasaki (Author), Yuriko Namioka (Author), Takefumi Ito (Author), Noriko Izumiyama (Author), Shin Fukui (Author), Akiko Watanabe (Author), Masayuki Kashima (Author), Masaaki Sano (Author), Takanobu Shioya (Author), Mamoru Miura (Author)
• Format: Book
• Published: Hindawi Limited, 2001-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Intracellular adhesion molecule-1 (ICAM-1)-mediated cell-cell adhesion is thought to play an important role at sites of inflammation. Recent evidence suggests that ICAM-1 surface expression on alveolar macrophages is increased in pulmonary sarcoidosis and that inflammatory granuloma formation is cha...