Role of ICAM-1 in the aggregation and adhesion of human alveolar macrophages in response to TNF-α and INF-γ

• Hauptverfasser: Masahiro Sasaki (Verfasst von), Yuriko Namioka (Verfasst von), Takefumi Ito (Verfasst von), Noriko Izumiyama (Verfasst von), Shin Fukui (Verfasst von), Akiko Watanabe (Verfasst von), Masayuki Kashima (Verfasst von), Masaaki Sano (Verfasst von), Takanobu Shioya (Verfasst von), Mamoru Miura (Verfasst von)
• Format: Buch
• Veröffentlicht: Hindawi Limited, 2001-01-01T00:00:00Z.
• Schlagworte: article
• Online-Zugang: Connect to this object online.

Intracellular adhesion molecule-1 (ICAM-1)-mediated cell-cell adhesion is thought to play an important role at sites of inflammation. Recent evidence suggests that ICAM-1 surface expression on alveolar macrophages is increased in pulmonary sarcoidosis and that inflammatory granuloma formation is cha...