An Exploratory Pilot Study of Changes in Global DNA Methylation in Patients Undergoing Major Breast Surgery Under Opioid-Based General Anesthesia

• मुख्य लेखकों: Francesca Felicia Caputi (लेखक), Lucia Carboni (लेखक), Laura Rullo (लेखक), Irene Alessandrini (लेखक), Eleonora Balzani (लेखक), Rita Maria Melotti (लेखक), Patrizia Romualdi (लेखक), Sanzio Candeletti (लेखक), Andrea Fanelli (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Frontiers Media S.A., 2021-09-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

This study aimed to investigate DNA methylation levels in patients undergoing major breast surgery under opioid-based general anesthesia. Blood samples were collected from eleven enrolled patients, before, during and after anesthesia. PBMC were isolated and global DNA methylation levels as well as D...