An Exploratory Pilot Study of Changes in Global DNA Methylation in Patients Undergoing Major Breast Surgery Under Opioid-Based General Anesthesia

• Hoofdauteurs: Francesca Felicia Caputi (Auteur), Lucia Carboni (Auteur), Laura Rullo (Auteur), Irene Alessandrini (Auteur), Eleonora Balzani (Auteur), Rita Maria Melotti (Auteur), Patrizia Romualdi (Auteur), Sanzio Candeletti (Auteur), Andrea Fanelli (Auteur)
• Formaat: Boek
• Gepubliceerd in: Frontiers Media S.A., 2021-09-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

This study aimed to investigate DNA methylation levels in patients undergoing major breast surgery under opioid-based general anesthesia. Blood samples were collected from eleven enrolled patients, before, during and after anesthesia. PBMC were isolated and global DNA methylation levels as well as D...