Simulating realistic patient profiles from pharmacokinetic models by a machine learning postprocessing correction of residual variability

Abstract We address the problem of model misspecification in population pharmacokinetics (PopPK), by modeling residual unexplained variability (RUV) by machine learning (ML) methods in a postprocessing step after conventional model building. The practical purpose of the method is the generation of r...

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Bibliographic Details
Main Authors: Christos Kaikousidis (Author), Robert R. Bies (Author), Aristides Dokoumetzidis (Author)
Format: Book
Published: Wiley, 2024-09-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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