Hepatotoxicity reports in the FDA adverse event reporting system database: A comparison of drugs that cause injury via mitochondrial or other mechanisms

• Asıl Yazarlar: Payal Rana (Yazar), Michael D. Aleo (Yazar), Xuerong Wen (Yazar), Stephen Kogut (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Elsevier, 2021-12-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Drug-induced liver injury (DILI) is a leading reason for preclinical safety attrition and post-market drug withdrawals. Drug-induced mitochondrial toxicity has been shown to play an essential role in various forms of DILI, especially in idiosyncratic liver injury. This study examined liver injury re...