תמונות העטיפה

Paraoxonase 2 Deficiency Causes Mitochondrial Dysfunction in Retinal Pigment Epithelial Cells and Retinal Degeneration in Mice

Although AMD is a complex disease, oxidative stress is a crucial contributor to its development, especially in view of the higher oxygen demand of the retina. Paraoxonase 2 (PON2) is a ubiquitously and constitutively expressed antioxidant protein that is found intracellularly associated with mitocho...

תיאור מלא

שמור ב:

מידע ביבליוגרפי
Main Authors:	Parameswaran Gangadharan Sreekumar (Author), Feng Su (Author), Christine Spee (Author), Elise Hong (Author), Ravikiran Komirisetty (Author), Eduardo Araujo (Author), Steven Nusinowitz (Author), Srinivasa T. Reddy (Author), Ram Kannan (Author)
פורמט:	ספר
יצא לאור:	MDPI AG, 2023-09-01T00:00:00Z.
נושאים:	article
גישה מקוונת:	Connect to this object online.
תגים:	הוספת תג אין תגיות, היה/י הראשונ/ה לתייג את הרשומה!

פריטים דומים

Glutathione Metabolism and the Novel Role of Mitochondrial GSH in Retinal Degeneration
מאת: Parameswaran G. Sreekumar, et al.
יצא לאור: (2021)

Human iPSC- and Primary-Retinal Pigment Epithelial Cells for Modeling Age-Related Macular Degeneration
מאת: Cody R. Fisher, et al.
יצא לאור: (2022)

Erythropoietin Gene Therapy Delays Retinal Degeneration Resulting from Oxidative Stress in the Retinal Pigment Epithelium
מאת: Manas R. Biswal, et al.
יצא לאור: (2021)

αB-Crystallin Peptide Fused with Elastin-like Polypeptide: Intracellular Activity in Retinal Pigment Epithelial Cells Challenged with Oxidative Stress
מאת: Sara Aly Attia, et al.
יצא לאור: (2023)

Effect of curcumin on aging retinal pigment epithelial cells
מאת: Zhu W, et al.
יצא לאור: (2015)

Transporter-Mediated Mitochondrial GSH Depletion Leading to Mitochondrial Dysfunction and Rescue with αB Crystallin Peptide in RPE Cells
מאת: Parameswaran G Sreekumar, et al.
יצא לאור: (2020)

Pharmacological inhibition of mitochondrial fission attenuates oxidative stress-induced damage of retinal pigmented epithelial cells
מאת: Tomohiro Yako, et al.
יצא לאור: (2021)

Evaluation for Retinal Therapy for RPE65 Variation Assessed in hiPSC Retinal Pigment Epithelial Cells
מאת: Benjamin M. Nash, et al.
יצא לאור: (2021)

Proteins Associated with Phagocytosis Alteration in Retinal Pigment Epithelial Cells Derived from Age-Related Macular Degeneration Patients
מאת: Audrey Voisin, et al.
יצא לאור: (2022)

Intracellular Uptake Mechanism of Lutein in Retinal Pigment Epithelial Cells
מאת: Yuki Sato, et al.
יצא לאור: (2013)

Retinal changes in an ATP-induced model of retinal degeneration
מאת: Felix Peter Aplin, et al.
יצא לאור: (2016)

The P2Y12 Receptor Antagonist Ticagrelor Reduces Lysosomal pH and Autofluorescence in Retinal Pigmented Epithelial Cells From the ABCA4-/- Mouse Model of Retinal Degeneration
מאת: Wennan Lu, et al.
יצא לאור: (2018)

Effects of the Macular Carotenoid Lutein in Human Retinal Pigment Epithelial Cells
מאת: Xiaoming Gong, et al.
יצא לאור: (2017)

Epitranscriptome Analysis of Oxidative Stressed Retinal Epithelial Cells Depicted a Possible RNA Editing Landscape of Retinal Degeneration
מאת: Luigi Donato, et al.
יצא לאור: (2022)

Vitamin D Attenuates Oxidative Damage and Inflammation in Retinal Pigment Epithelial Cells
מאת: Ali Mohammad Tohari, et al.
יצא לאור: (2019)

Retinal Pigment Epithelial Cell Line with Fast Differentiation and Improved Barrier Properties
מאת: Laura Hellinen, et al.
יצא לאור: (2019)

Acute retinal pigment epitheliitis and dosimetric follow-up: a case report
מאת: Tetiana Babenko, et al.
יצא לאור: (2024)

Lipoic Acid and Progesterone Alone or in Combination Ameliorate Retinal Degeneration in an Experimental Model of Hereditary Retinal Degeneration
מאת: Dolores T. Ramírez-Lamelas, et al.
יצא לאור: (2018)

Oxidative Stress and Inflammation in Retinal Degeneration
מאת: Ravirajsinh N. Jadeja, et al.
יצא לאור: (2021)

Effects of Resvega on Inflammasome Activation in Conjunction with Dysfunctional Intracellular Clearance in Retinal Pigment Epithelial (RPE) Cells
מאת: Niina Bhattarai, et al.
יצא לאור: (2021)

Mouse Idh3a mutations cause retinal degeneration and reduced mitochondrial function
מאת: Amy S. Findlay, et al.
יצא לאור: (2018)

Functions and Diseases of the Retinal Pigment Epithelium
מאת: Song Yang, et al.
יצא לאור: (2021)

Diacerein Inhibits Myopia Progression through Lowering Inflammation in Retinal Pigment Epithelial Cell
מאת: Peng-Tai Tien, et al.
יצא לאור: (2021)

Effects of Vitamin D3 and Meso-Zeaxanthin on Human Retinal Pigmented Epithelial Cells in Three Integrated in vitro Paradigms of Age-Related Macular Degeneration
מאת: Francesca Lazzara, et al.
יצא לאור: (2021)

Retinal pigment epithelium degeneration caused by aggregation of PRPF31 and the role of HSP70 family of proteins
מאת: Lourdes Valdés-Sánchez, et al.
יצא לאור: (2019)

Correlation between SD-OCT, immunocytochemistry and functional findings in a pigmented animal model of retinal degeneration
מאת: Nicolás eCuenca, et al.
יצא לאור: (2014)

Retinal Vascular Degeneration in the Transgenic P23H Rat Model of Retinitis Pigmentosa
מאת: Laura Fernández-Sánchez, et al.
יצא לאור: (2018)

A Safe GDNF and GDNF/BDNF Controlled Delivery System Improves Migration in Human Retinal Pigment Epithelial Cells and Survival in Retinal Ganglion Cells: Potential Usefulness in Degenerative Retinal Pathologies
מאת: Alicia Arranz-Romera, et al.
יצא לאור: (2021)

Cytoprotective Effects of Punicalagin on Hydrogen-Peroxide-Mediated Oxidative Stress and Mitochondrial Dysfunction in Retinal Pigment Epithelium Cells
מאת: Maria Elisabetta Clementi, et al.
יצא לאור: (2021)

Different Effects of Metformin and A769662 on Sodium Iodate-Induced Cytotoxicity in Retinal Pigment Epithelial Cells: Distinct Actions on Mitochondrial Fission and Respiration
מאת: Chi-Ming Chan, et al.
יצא לאור: (2020)

Protein-Mediated Carotenoid Delivery Suppresses the Photoinducible Oxidation of Lipofuscin in Retinal Pigment Epithelial Cells
מאת: Alexey N. Semenov, et al.
יצא לאור: (2023)

TRAP1 Is Expressed in Human Retinal Pigment Epithelial Cells and Is Required to Maintain their Energetic Status
מאת: Inês Ramos Rego, et al.
יצא לאור: (2023)

Comparison of Antioxidant Properties of Dehydrolutein with Lutein and Zeaxanthin, and their Effects on Cultured Retinal Pigment Epithelial Cells
מאת: Małgorzata B. Różanowska, et al.
יצא לאור: (2021)

Oxidative stress induces lysosomal membrane permeabilization and ceramide accumulation in retinal pigment epithelial cells
מאת: Kevin R. Zhang, et al.
יצא לאור: (2023)

Establishment of a drug evaluation model against light-induced retinal degeneration using adult pigmented zebrafish
מאת: Yuichi Saito, et al.
יצא לאור: (2016)

Impaired retinal vasodilator response to acetylcholine in a rat model of NMDA-induced retinal degeneration
מאת: Asami Mori, et al.
יצא לאור: (2015)

Eucalyptol Inhibits Amyloid-β-Induced Barrier Dysfunction in Glucose-Exposed Retinal Pigment Epithelial Cells and Diabetic Eyes
מאת: Dong Yeon Kim, et al.
יצא לאור: (2020)

Endothelial Notch Signaling Regulates the Function of the Retinal Pigment Epithelial Barrier via EC Angiocrine Signaling
מאת: Yali Niu, et al.
יצא לאור: (2023)

PPARδ Inhibits Hyperglycemia-Triggered Senescence of Retinal Pigment Epithelial Cells by Upregulating SIRT1
מאת: Eun Ji Lee, et al.
יצא לאור: (2022)

HIF-1α-dependent upregulation of angiogenic factors by mechanical stimulation in retinal pigment epithelial cells
מאת: Atsushige Ashimori, et al.
יצא לאור: (2024)