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Paraoxonase 2 Deficiency Causes Mitochondrial Dysfunction in Retinal Pigment Epithelial Cells and Retinal Degeneration in Mice

Although AMD is a complex disease, oxidative stress is a crucial contributor to its development, especially in view of the higher oxygen demand of the retina. Paraoxonase 2 (PON2) is a ubiquitously and constitutively expressed antioxidant protein that is found intracellularly associated with mitocho...

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Main Authors: Parameswaran Gangadharan Sreekumar (Author), Feng Su (Author), Christine Spee (Author), Elise Hong (Author), Ravikiran Komirisetty (Author), Eduardo Araujo (Author), Steven Nusinowitz (Author), Srinivasa T. Reddy (Author), Ram Kannan (Author)
Format: Book
Published: MDPI AG, 2023-09-01T00:00:00Z.
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